Amoxicillin + Clavulanic Acid

Combinations of Amoxicillin and Clavulanic Acid


  • Amoxicillin 500 mg. & Clavulanic Acid 125 mg. Tablets
  • Amoxicillin 250 mg. & Clavulanic Acid 125 mg. Tablets
  • Amoxicillin 200 mg. & Clavulanic Acid 28.5 mg. Tablets
  • Amoxicillin 200 mg. & Clavulanic Acid 28.5 mg. per 5 ml. Dry Syrup
  • Amoxicillin 400 mg. & Clavulanic Acid 57 mg. per 5 ml. Dry Syrup
  • Amoxicillin 250 mg. & Clavulanic Acid 62.5 mg. per 5 ml. Dry Syrup
  • Amoxicillin 125 mg. & Clavulanic Acid 31.25 mg. per 5 ml. Dry Syrup

Amoxicillin and Clavulanic Acid: An oral antibacterial combination consisting of the semisynthetic antibiotic amoxicillin and the β-lactamase inhibitor clavulanic acid.

EXECUTIVE SUMMARY
Drug Name Amoxicillin and Clavulanic Acid
Mechanism of Action

Amoxicillin: It inhibits cross-linkage between the linear peptidoglycan polymer chains that make up a major component of the cell walls of both Gram-positive and Gram-negative bacteria.

Clavulanic Acid: It is a β-lactam structurally related to the penicillins and possesses the ability to inactivate a wide variety of β-lactamases by blocking the active sites of these enzymes.

Indication Treatment of patients with community-acquired pneumonia or acute bacterial sinusitis due to confirmed, or suspected β-lactamase−producing pathogens and S. pneumoniae with reduced susceptibility to penicillin
Form

Tablets (Amoxicillin/Clavulanic Acid) : 500/125 mg , 250/125 mg , 200/28.5 mg

Dry Syrup (Amoxicillin/Clavulanic Acid) : 200/28.5mg